05 December 2013
Posted in Pearls in Ophthalmology
By Brooke Strickland
In this study, researchers sought to evaluate the safety and effectiveness of intracameral triamcinolone acetonide in phacotrabeculectomy. In the randomized trial, patients that had combined trabeculectomy and cataract surgery were examined and enrolled in a two year period (March 2010 to January 2012). The patients (a total of 126 with an average age of 64) were divided into four groups. Group A was given intracameral triamcinolone acetonide (0.5 mg), Group B received triamcinolone acetonide (1.0 mg), and Group C received triamcinolone acetonide (2.0 mg). Group D served as the control group and received nothing.
The results showed that the patients that were treated with the triamcinolone acetonide had better vision overall and less inflammation in the anterior chamber than those that didn’t receive the medication. All patients had a conventional 2-side trabeculectomy and phacoemulsification with foldable posterior chamber intraocular lens implantation. Visual acuity and clinical indexes of anterior segment inflammation were assessed 1, 7, 14, and 28 days postoperatively. (1)
What to take away from the study: Intracameral injection of triamcinolone acetonide in phacotrabeculectomy resulted in a significant reduction in aqueous inflammation and helped improve vision significantly.
1. Wang, Bingsong, PhD, Dong, Ning, MD, Xu, Bing, MD, Liu, Jing, MD, Xiao, Lin, MD, PhD. “Efficacy and safety of intracameral triamcinolone acetonide to control postoperative inflammation after phacotrabeculectomy.” Journal of Cataract & Refractive Surgery. Volume 39, Issue 11, Pages 1691-1697. November 2013. Accessed online November 29, 2013. http://www.jcrsjournal.org/article/S0886-3350%2813%2900879-1/abstract
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